Prof. HUANG Shilin holds that acute promyelocytic leukemia（ APL） attacks because of deficiency of vital Qi and internal retention of pathogenic toxin. The essence of the disease is pathogen excess and root asthenia.Prof. HUANG puts forward that expulsing pathogen and recuperating vital Qi is the principle to treat APL. Xionghuang [realgar

雄黄] is the sovereign herb. Qingdai [Indigo Naturalis

青黛]is the minister herb. Danshen [Radix Salviae Miltiorrhizae

丹参]and Taizishen [Radix Pseudostellariae

太子参]are the assistant and envoy herbs. So Fufang Huangdai Tablet（ 复方黄黛片） is composed. Prof. HUANG types APL as blazing poison-heat type

blood stasis mass type and deficiency of Qi and Yin type. APL includes induced remission stage and remission stage. Prof.HUANG treats APL according to different syndrome types and different stages.