ZHOU Xin, XUE Wenda, WU Haoxin, et al. Possibility and Prospect of Application of Association Study on Genomewide and Phenome-wide in Chinese Medicine Researches[J]. Journal of Traditional Chinese Medicine2016, 57(14): 1191-1194.
ZHOU Xin, XUE Wenda, WU Haoxin, et al. Possibility and Prospect of Application of Association Study on Genomewide and Phenome-wide in Chinese Medicine Researches[J]. Journal of Traditional Chinese Medicine2016, 57(14): 1191-1194.DOI: 10.13288/j.11-2166/r.2016.14.006.
Chinese medicine syndrome differentiation treatment emphasizes individualized treatment on patients
which is similar to precision treatment proposed by modern medicine. Chinese medicine constitution and syndrome is determined partly by natural endowment
which means that inheritance plays an important role. Genomewide association study could correlate gene mutation with disease or physiological characteristics directly. Phenomewide association study could further find out different phenotypes influenced by specific genetic variation site. In future Chinese medicine researches
molecular genetic basis
which is influenced by certain constitution
syndrome and disease-syndrome combination syndrome treatment
might be differentiated from genomewide aspect by genomewide association study and phenomewide association study. The essence of modern biology of Chinese medicine syndrome differentiation treatment might be revealed. This paper might provide reference for improving the precision and stability of Chinese medicine diagnosis and treatment.