Objective To explore the curative effects of Ginkgo Leaf Capsules（ 银杏叶胶囊） combined with aripiprazole in the treatment of schizophrenia. Methods One hundred and twenty-one patients with schizophrenia were randomly divided into an observation group and a control group

with 62 cases in each. Both groups were given aripiprazole orally disintegrating tablet

5 mg each time

twice per day from the first to the fourth day

and 10 mg each time

twice every day from the fifth day. The observation group was added with Ginkgo Leaf Capsules

0. 25 g each time

three times per day. The two groups were both treated for 12 weeks. Evaluation was conducted with PANSS scale

Wisconsin Card Sorting Test（ WCST） and auditory attention test（ ATT） scale before treatment and on the 4th

8th

and 12 th weekends after treatment

and the clinical curative effects were also evaluated. Results The total effective rate was 88. 52% in the observation group while 81. 67% in the control group

with no significant difference between the two groups（ P > 0. 05）. There was no significant difference in grading in PANSS scale between the two groups（ P > 0. 05）. After 8-weeks treatment

all scales of WCST and AAT in the observation group improved remarkably compared with that before treatment（ P < 0. 05）; But in the control group

only total trials

persistent errors and random errors in WSCT scale

total correct number and missing number in the ATT scale remarkably improved（ P <0. 05）; The complete classification number in WSCT scale and missing number in the ATT scale in the observation group were both superior to that in the control group（ P < 0. 05）. After being treated for 12 weeks

all types of grading in WCST and AAT in both groups improved remarkably compared with that before treatment（ P < 0. 05）. Total trials

random errors and complete classification number in WSCT scale

and total correct number

error number and missing number in ATT scale in the observation group were all remarkably superior to that in the control group（ P <0. 05）. Conclusion Ginkgo Leaf Capsules combined with aripiprazole has reliable effects in the treatment of schizophrenia

and could improve cognitive function of patients.