Objective To explore the possible functional mechanism of Jinxin Oral Liquid（ 金欣口服液） on respiratory syncytial virus（ RSV） pneumonia. Methods Forty-eight 48 BALB / c mice were randomly divided into a normal group

a RSV pneumonia group

and a Jinxin Oral Liquid group

with 16 mice in each. The RSV pneumonia group and the Jinxin Oral Liquid group accepted RSV suspension nasal drip to infect mice to build RSV pneumonia model. The Jinxin Oral Liquid group was given Jinxin Oral Liquid 27. 6 g /（ kg·d） for gavage. The normal group and the RSV pneumonia group were given saline with equal dose for gavage. Five mice in each group were executed for pathological examination on the fourth day. Urine sample of other mice were collected on the sixth day respectively and GC-MS was adopted to examine urine metabolites and the changes of its relative levels. Results There were mesenchymal multifocal inflammatory infiltrations

slight hyperaemia and remarkable thickness in alveolar wall in the lung of RSV pneumonia model mice. The lung inflammation in the Jinxin Oral Liquid group remarkably decreased compared with that in the RSV pneumonia group. There were 38 types of metabolites examined in urine of mice in the RSV pneumonia group

among which lactic acid

glycine

palmitic acid and stearic acid were variant metabolites. In the RSV pneumonia group

the relative levels of lactic acid

glycine

palmitic acid and stearic acid were remarkably higher than that in the normal group and the Jinxin Oral Liquid group（ P < 0. 05）. Conclusion Jinxin Oral Liquid could cure RSB pneumonia by means of regulating energy metabolism

amino acid metabolism and fatty acid metabolism.