At present

symptoms

signs and biological indicators are mainly observed for the evaluation of Chinese medical clinical effect

but it is lack of objective endpoint criteria. Therefore

to construct endpoint criteria that can reflect the advantages of "complex intervention"of Chinese medicine is an urgent business in Chinese medical research. Based on the data type and characteristics of endpoint criteria

the mathematical models including the weighting method of information content and independence

logistic regression analysis

factor and principal component analysis and their applicability were analyzed. And the principal component analysis was introduced into calculating the objective weight of each indicator at different time. Combined with occurrence frequency of each indicator

the normalization method of multiplier compounding was used to confirm comprehensive weight of each indicator at different time. Then combined with clinical significance

the endpoint criteria for evaluation of Chinese medical clinical effect was established. Using this method may not only reflect the objectivity of endpoint criteria

but also highlight its different importance

sequence and incidence rate

and may provide scientific basis for outcome evaluation of Chinese medical clinical effect.