Objective To explore the syndromes and the meidication regulatity of famous doctors treating chronic bronchitis in Jiangsu

Zhejiang and Shanghai. Methods The herbs used and related symptoms in treating chronic bronchitis in Jiangsu

Zhejiang and Shanghai were collected from pulmonary disease database established by national clinical research base construction project. After the herbs and symptom names were screened and normatively approached

the symptom and herb implicit structure models were established respectively. Different hidden classes in implicit structure were interpreted one by one combined with professional knowledge. At last

syndrome elements

herbs’ tropism of taste and major function were summarized and extracted. Meanwhile

herbs and symptoms were made association rule data mining. Results Totally

354 medical records were included

containing 651 symptoms and 304 herbs. Symptom implicit structure model was established by 102 explicit variables of symptom

tongue and pulse. Thirteen hidden variables

26 hidden classes and 3 integrated clustering models were got. Herb implicit structure model was established by 129 herbs. Thirty hidden variables

60 hidden classes and 9 integrated clustering models were got. After herbs and symptoms association rule data mining

47 bigeminal groups

149 triple groups and132 quadrigeminal groups were got. Conclusion The causes of chronic bronchitis in Jiangsu

Zhejiang and Shanghai were mostly phlegm-dampness（ turbidity）

phlegm-fluid retention and phlegm-heat. Main syndromes were syndrome of turbid phlegm obstructing lung

syndrome of phlegm-turbidity obstructing middle-jiao and syndrome of phlegm-heat obstructing lung. Frequently used herbs of famous doctors treating chronic bronchitis were Xixin [Herba Asari]

Guizhi [Ramulus Cinnamomi ]

Sangbaipi [Cortex Mori]. Frequently used herb groups were Pingdimu（ Japanese ardisia） with Gonglaoye [Folium Ilex] and Zeqi（ wartwort） with Zhishi [Fructus Aurantii Immaturus]and Shegan [Rhizoma Belamcandae].