Objective To observe clinical curative effects and safety of fumigating and washing with Langdu Fang（ 狼毒方） combined with compound Qingdai Capsule（ 复方青黛胶囊） orally treating psoriasis vulgaris of blood heat syndrome. Methods Randomly divided 61 patients with psoriasis into the treatment group（ 31 cases） and the control group（ 30 cases）. The treatment group was fumigated and washed with Langdu Fang combined with compound Qingdai Capsule for oral administration. The control group was given compound Qingdai Capsule for oral administration. Treatment courses in the two groups were both 8 weeks. Observed scores of Psoriasis Area and Severity Index（ PASI） of patients in two groups before and after treatment. Evaluated the clinical curative effect

and the relapse of well-healed patients in the two groups at 3 and 6 months after stopping medicine. Results PASI scores after treatment in the two groups all decreased compared with that before treatment

and PASI scores after treatment in the treatment group was remarkably lower than those in the control group（ P < 0. 05）. Curative rate in the treatment group was 83. 87% and the total effective rate was 93. 55%; those of the control group were respectively 60. 00% and86. 67%. The curative rate in the treatment group was higher than that in the control group（ P < 0. 05）. The difference of the total effective rates in two groups had no statistical significance（ P > 0. 05）. Relapse rates in the treatment group at 3 and 6 months after stopping medicine were both 7. 14%

while 20. 00% and 40. 00% in the control group respectively. The total relapse rate in the treatment group was remarkably lower than that in the control group（ P < 0. 05）. Conclusion The clinical curative effect of fumigating and washing with Langdu Fang combined with compound Qingdai Capsule for orally treating psoriasis vulgaris of blood heat syndrome were superior to compound Qingdai Capsule alone. The safety of combination therapy seems to be good.