Objective To evaluate the clinical curative effect and safety of Ganjie Bingmei tablet（ 甘桔冰梅片）in treating acute pharyngitis with wind heat invading lung syndrome. Methods Using multi-center

randomized

double-blind

placebo parallel controlled clinical trial design

240 patients were included in which 235 cases completed

with 119 cases in the treatment group and 116 cases in the control group. The treatment group and the control group were treated by the Ganjie Bingmei tablet and placebo respectively

with 0. 4 g each time

4 times per day

totally for 5 days. Observed the comprehensive curative effect of the two groups and the curative effect of Chinese medicine symptoms（ including sore throat

dry pharynx and burning sensation

pharyngeal mucosal hyperemia

dysphagia）

and recorded the adverse reactions. Results In the treatment group

the clinical curative rate was13. 5%

and the total effective was 87. 4%; in the control group

the clinical curative rate was 7. 8%

and the total effective was 54. 3%. There were statistical differences in curative effect between the the two groups（ P < 0. 05）

and the curative effect in the treatment group was better than that in the control group. The improvement rate of pharyngalgia in the treatment group was 89. 9%

and that in the control group was 61. 2%. The improvement rate of dry pharynx and burning sensation in the treatment group was 88. 7%

and that in the control group was 52. 6%. The improvement rate of pharyngeal mucosal congestion in the treatment group was 73. 9%

and that in the control group was 48. 3%. The disappearance rate of dysphagia in the treatment group was 88. 7%

and that in the control group was 76. 6%

thus

the improvement rate of the symptoms were better than those in the control group（ P < 0. 05 or P < 0. 01）. Ganjie Bingmei tablet had no obvious toxic side effects and adverse reactions. Conclusion Ganjie Bingmei tablet in treating acute pharyngitis with wind heat invading lung syndrome seems to have definite curative effect

and the safety appears good.