The clinical symptoms of late onset hypogonadism（ LOH） are complex and diverse

which has close relation to a variety of diseases.As for the treatment

Chinese medicine has some advantages compared with modern medicine single androgen replacement therapy.The authors put forward that the core pathogenesis of LOH is kidney deficiency and liver depression.The start factor is kidney deficiency.The pathogenic pivot is liver depression.Qi and blood should be paid appropriate attention in LOH treatment.The authors hold that invigorating the kidney

dispersing stagnated liver Qi and coordinating Qi-blood is the entry point in treating LOH.