天津中医药大学第一附属医院
纸质出版:2017
移动端阅览
[1]许颖智,张军平,任淑女,荣杰,杨锡燕.不同中医干预模式对冠心病心绞痛患者症状及生存质量的影响[J].中医杂志,2017,58(06):493-497.
XU Yingzhi, ZHANG Junping, REN Shunv, et al. The Effect of Different Chinese Medicine Intervening Models on Symptoms and Quality of Life in Older Patients with Angina Pectoris[J]. Journal of Traditional Chinese Medicine2017, 58(6): 493-497.
[1]许颖智,张军平,任淑女,荣杰,杨锡燕.不同中医干预模式对冠心病心绞痛患者症状及生存质量的影响[J].中医杂志,2017,58(06):493-497. DOI: 10.13288/j.11-2166/r.2017.06.011.
XU Yingzhi, ZHANG Junping, REN Shunv, et al. The Effect of Different Chinese Medicine Intervening Models on Symptoms and Quality of Life in Older Patients with Angina Pectoris[J]. Journal of Traditional Chinese Medicine2017, 58(6): 493-497. DOI: 10.13288/j.11-2166/r.2017.06.011.
目的观察不同中医干预模式对老年冠心病心绞痛患者的临床疗效。方法将164例老年冠心病心绞痛气虚血瘀证和气滞血瘀证患者随机分为辨证论治组和辨病通治组
每组82例。在西医常规治疗基础上
辨证论治组中气虚血瘀证患者予芪参益气滴丸0.9 g、气滞血瘀证患者予复方丹参滴丸0.27 g
每日3次口服;辨病通治组均予活血保心丸9 g
每日2次口服。两组均治疗4周。两组治疗前后采用西雅图心绞痛调查量表(SAQ)评价生存质量
治疗前及治疗后2、4周进行记录症状积分
并在治疗后评价临床疗效。结果辨证论治组临床疗效总有效率为84.15%
显著高于辨病通治组的60.98%(P<0.05)
且辨证论治组中气虚血瘀证和气滞血瘀证患者疗效均分别优于辨病通治组的相应证型(P<0.05或P<0.01)。辨证论治组SAQ评分中躯体活动受限程度、心绞痛发作情况评分及总积分均高于辨病通治组(P<0.05或P<0.01)。治疗4周后两组症状积分均较治疗前显著降低
且辨证论治组低于辨病通治组(P<0.05)。结论与辨病通治干预模式比较
辨证论治干预模式治疗老年冠心病心绞痛能够更好地改善心绞痛症状及生存质量。
Objective To observe clinical curative effect of different Chinese medicine intervening models in older patients with angina pectoris.Methods Totally 164 older patients with angina pectoris of Qi deficiency and blood stasis syndrome and Qi stagnation and blood stasis syndrome were randomly divided into a treatment based on syndrome differentiation group and a conventional treatment based on disease differentiation group
with 82 cases in each.In the treatment based on syndrome differentiation group
in addition to conventional treatment of western medicine
patient of Qi deficiency and blood stasis syndrome were given 0.9 g of Qishen Yiqi Droplet( 芪参益气滴丸) orally
and patients of Qi stagnation and blood stasis syndrome were given 0.27 g of Compound Danshen Dripping Pills( 复方丹参滴丸) orally
three times per day.the common treatment based on disease differentiation group was all given 9 g of Huoxue Baoxin Pill( 活血保心丸) orally
twice per day.Two groups were both treated for 4 weeks.Before and after treatment
Seattle Angina Questionnaire( SAQ) was adopted to evaluate quality of life.Syndrome scores were recorded before treatment and at 2 or 4 weeks after treatment.Clinical curative effects were evaluated after treatment.Results The total clinical curative effect in the treatment based on syndrome differentiation group was 84.15%
which was significantly higher than 60.98% in the common treatment based on disease differentiation group( P <0.05).And the curative effect rates in patients of Qi deficiency and blood stasis syndrome and Qi stagnation and blood stasis syndrome in the treatment based on syndrome differentiation group were all superior to those of the corresponding syndromes in the common treatment based on disease differentiation group( P < 0.05 or P < 0.01).Physical limitation degree
angina condition score and total score in SAQ in the treatment based on syndrome differentiation group were all higher than those in the common treatment based on disease differentiation group( P < 0.05 or P <0.01).After 4-week treatment
symptom scores in the two groups both significantly decreased compared with those before treatment
and the symptom scores in the treatment based on syndrome differentiation group were lower than those in the common treatment based on disease differentiation group( P < 0.05).Conclusion In treating aged angina pectoris
compared with the common treatment based on disease differentiation model
treatment based on syndrome differentiation model could better improve symptoms of angina and quality of life.
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