By summarizing and comparing the nationally unified and complied diagnostics of traditional Chinese medicine textbooks

the authors explore and analyze the development of etiology syndrome differentiation connotation in Chinese medicine syndrome differentiation system and the causes of that it is gradually replaced by disease nature syndrome differentiation. The authors think that the form of concept pathogeny in Chinese medicine is based on western medicine theoretical mode. However

western medicine theoretical mode could not accord with the characteristics of Chinese medicine completely

which expands the connotation of pathogeny in Chinese medicine to disease nature field.