Objective To observe the clinical efficacy of Yiqi Huoxue Jiedu Fang in treating angina pectoris patients after percutaneous coronary intervention（PCI）. Methods Ninety one cases of angina pectoris patients after PCI were randomly divided into treatment group（46 cases） and control group（45 cases）. The two groups were both given basic treatment. In addition

the control group was given Yangxinshi Tablet（养心氏片）

1. 8 g each time

three times daily. Treatment group was given Yiqi Huoxue Jiedu Fang

1 dose daily. The two groups both were treated for 4 weeks. After treatment

the efficacy for angina pectoris

electrocardiogram and Chinese medical syndrome in the two groups were observed separately. Changes in levels of total cholesterol（TC）

triglyceride（TG）

low density lipoprotein cholesterol（LDL-C）

high density lipoprotein cholesterol（HDL-C）

high sensitivity C reactive protein（hs-CRP） and interleukin-6（IL-6） were separately tested before and after treatment. Results The total effective rates of the efficacy for angina pectoris

electrocardiogram and Chinese medicine syndrome in treatment group were86. 96%

69. 57% and 93. 48% respectively. The effective rates in control group were 68. 89%

46. 67% and77. 78% respectively. The effective rates in treatment group were all higher than those in control group（P < 0. 05 or P < 0. 01）. In the two groups

the levels of TC

TG

LDL-C

hs-CRP and IL-6 after treatment were lower than those before treatment

and the level of HDL-C after treatment was higher than that before treatment（P < 0. 01）. After treatment

the levels of hs-CRP and IL-6 were significantly decreased in treatment group compared with those in control group（P < 0. 01）. Conclusion Yiqi Huoxue Jiedu Fang could alleviate angina pectoris after PCI and restrain inflammation to protect the function of vascular endothelium.