MA Rong, GAO Ronglin, QI Wensheng, et al. A Double Blind,Randomized Controlled Trial on Bainiu Xuanfei Decoction( 白牛宣肺汤) in Treating Postinfectious Cough[J]. Journal of Traditional Chinese Medicine2017, 58(20): 1755-1759.
MA Rong, GAO Ronglin, QI Wensheng, et al. A Double Blind,Randomized Controlled Trial on Bainiu Xuanfei Decoction( 白牛宣肺汤) in Treating Postinfectious Cough[J]. Journal of Traditional Chinese Medicine2017, 58(20): 1755-1759.DOI: 10.13288/j.11-2166/r.2017.20.012.
Objective To evaluate the clinical efficacy and safety of Bainiu Xuanfei Decoction( 白牛宣肺汤) in treating postinfectious cough. Methods Seventy postinfectious cough patients with syndrome of endogenous stagnated heat and remaining exogenous pathogen were randomly divided into a Chinese medicine group and a control group
with 35 cases in each group. Chinese medicine group was given Bainiu Xuanfei Decoction and montelukast sodium tablet simulants orally. The control group was given Bainiu Xuanfei Decoction simulants and montelukast sodium tablets orally. Both groups were treated for 7 days and followed up for 7 days. Clinical efficacy and safety were evaluated after follow-up. Results After treatment
daytime and night cough symptom scores and visual analogue scale( VAS score) in Chinese medicine group were all obviously lower than those before treatment( P < 0. 001). Daytime cough symptom scores and VAS score in Chinese medicine group were all obviously lower than those in control group( P <0. 05). The effective rate in Chinese medicine group was 90. 91%
which was obviously higher than 62. 50% in control group( P < 0. 05). After treatment
overall symptom score in Chinese medicine group was obviously lower than that before treatment( P < 0. 001). Composite symptom score in Chinese medicine group was obviously lower than that in control group( P < 0. 01). The onset time of stopping the cough
remission time of cough and healing time of cough in Chinese medicine group were all obviously shorter than those in control group( P < 0. 01). Recurrence rate in Chinese medicine group was 12. 50%
which was lower than 40. 00% in control group( P < 0. 05). There were no adverse events in the two groups. Conclusion Bainiu Xuanfei Decoction seems to have notable curative effect
low recurrence rate and good security in the treatment of postinfectious cough.