Peripheral neurotoxicity is one of the common side effects of chemotherapy. Combined with the basic theory of Chinese medicine

this article raises that the pathogenesis of peripheral neurotoxicity caused by chemotherapy is that spleen-kidney deficiency and subsequent resource lack for generation of Qi and blood

combined with that chemotherapy drugs severely injure Qi and blood

turbid phlegm and stasis obstruct channels and collaterals. The root is Qi and blood deficiency

and the branch is internal toxins such as turbid phlegm and stasis. According to this

two basic therapeutic principles are determined

which are supplementing deficiency and resolving toxins. The key is reinforcing kidney

dissolving stasis and resolving toxins

and the specific methods are fortifying spleen and reinforcing kidney; regulating and reinforcing liver and kidney; invigorating blood

dissolving stasis and resolving toxins; dissipating cold

unblocking collaterals and resolving toxins as well as dispelling wind

eliminating dampness and resolving toxins.