Objective To observe the medication characteristics of Qingkailing Injection（ 清开灵注射液） in the real world. Methods Collected inpatients information in hospital management system（ HIS） of 16 three grade first class hospitals. According to integrated data warehouse construction model

integrated them into the Qingkailing Injection HIS data warehouse. Conducted descriptive analysis on basic information

patient information

diagnosis and syndrome differentiation of Chinese medicine

and drug combination information in 12 385 patients having used Qingkailing Injection. Then compared the information with the drug instructions. Results Patients using Qingkailing Injection were mostly aged 45

65

accounted for 35. 14%; acute and critical patients in admission accounted for 42. 65%; the top two highest incidence of morbidity and mortality in patients using Qingkailing Injection was in winter solstice and slight cold; patients conforming to western diagnosis in drug instruction accounted for 36. 84%; patients conforming to main symptom of Chinese medicine in drug instruction accounted for 42. 35%; the single dose of 49. 64% patients using Qingkailing Injection was 30

40 ml. Conclusion Qingkailing Injection is mostly used in middle-aged and elderly patients. Some doctors use drugs not according to the recommended dosage and indications on the instruction. Drug combination is common but there may be drug-induced risk.