Clinical Observation on Dangfei Liganning Capsule ( 当飞利肝宁胶囊) Combined with Chinese Herbal Tea in Treating 37 Cases of Non-alcoholic Fatty Liver with Liver Constraint and Spleen Deficiency and Damp-heat Accumulation Syndrome
HONG Huiwen, ZHAO Xiaowei, ZHANG Simiao, et al. Clinical Observation on Dangfei Liganning Capsule ( 当飞利肝宁胶囊) Combined with Chinese Herbal Tea in Treating 37 Cases of Non-alcoholic Fatty Liver with Liver Constraint and Spleen Deficiency and Damp-heat Accumulation Syndrome[J]. Journal of Traditional Chinese Medicine2018, 59(3): 227-230.
HONG Huiwen, ZHAO Xiaowei, ZHANG Simiao, et al. Clinical Observation on Dangfei Liganning Capsule ( 当飞利肝宁胶囊) Combined with Chinese Herbal Tea in Treating 37 Cases of Non-alcoholic Fatty Liver with Liver Constraint and Spleen Deficiency and Damp-heat Accumulation Syndrome[J]. Journal of Traditional Chinese Medicine2018, 59(3): 227-230.DOI: 10.13288/j.11-2166/r.2018.03.012.
Objective To observe the clinical effect of Dangfei Liganning Capsule( 当飞利肝宁胶囊
DLC) combined with Chinese herbal tea in the intervention of non-alcoholic fatty liver with liver constraint and spleen deficiency and damp-heat accumulation syndrome. Methods Seventy patients with non-alcoholic fatty liver of liver constraint and spleen deficiency and damp-heat accumulation syndrome were randomized into the treatment group( 37 cases)and the control group( 33 cases). The treatment group was given DLC combined with Chinese herbal tea which could soothe the liver and strengthen the spleen
the control group was given Atorvastatin Calcium Tablets( 10 mg per day).Both groups were treated for 3 courses with 4 weeks as a course of treatment. Before and after treatment
liver function and serum lipids including alanine transaminase( ALT)
aspartate transaminase( AST)
total bilirubin( TBi L)
total cholesterol( TC) and triglyceride( TG) were detected. After treatment
the efficacy of clinical syndrome was determined
while the incidence of adverse reactions was observed. Results After treatment
the total effective rate of clinical syndromes was 97. 30% in the treatment group
superior to 72. 72% in the control group( P < 0. 05). After treatment
the levels of ALT
AST
TBi L
TG and TC in both groups were lower than those before treatment( P <0. 05)
and the levels of ALT
AST and TBi L in the treatment group was lower than those in the control group( P <0. 05). The incidence of adverse reactions in the treatment group was 2. 70%
which was lower than 18. 18% in the control group( P < 0. 05). Conclusion DLC combined with Chinese herbal tea seems have good efficacy on nonalcoholic fatty liver with liver constraint and spleen deficiency and damp-heat accumulation syndrome
can improve liver function and has the lipid-lowering effect with good safety.