Objective To observe the clinical efficacy of combined therapy of Runfu Qufeng Decoction（ RFQF）（ 润肤祛风汤） in the treatment of senile eczema with blood deficiency and wind dryness. Methods Totally 120 cases of senile chronic eczema with blood deficiency and wind dryness syndrome were randomly divided into 60 cases each in the treatment group and the control group. The control group was treated with Broussonetia papyrifera leaf bath plus polyethylene glycol for external application

and desonide cream external use

twice a day. On the basis of the control group

the treatment group was given oral administration of RFQF Decoction

1 dose a day

10 days as a treatment course for 3 treatment courses. The changes of symptom scores before treatment and 2

3 treatment courses were observed. The clinical efficacy was determined after 3 courses of treatment. The recurrence was followed up after 3 months. Results The total effective rate of the treatment group and the control group was 93. 3%

81. 7% respectively. The treatment group was significantly supperior to the control group（ P < 0. 05）. After 2 courses of treatment and 3 courses of treatment

the symptom scores in the treatment group and the control group were all lower than those before treatment（ P < 0. 05）. After 3 course of treatment

the symptom scores of the treatment group and the control group were all lower than those of the 2 courses（ P < 0. 05）. After 2 courses of treatment and 3 courses of treatment

the symptom scores in the treatment group were significantly lower than those in the control group（ P < 0. 05）. There were no obvious adverse reactions in both groups. After 3 months

the recurrence rate of the treatment group was9. 4%

and that of the control group was 38. 1%. The treatment group was lower than the control group（ P < 0. 05）.Conclusion The therapeutic effect of RFQF Decoction in the treatment of senile eczema with blood deficiency and wind dryness syndrome has high clinical effect

no adverse reaction

and is safe and reliable.