Professor RUAN Shiyi holds that although the location of coronary heart disease（ CHD） is at heart

the key pathogenesis of CHD is intermingled phlegm

blood

and heat. Based on traditional Chinese medicine theory

he proposed the conception of "stasis in vessel"

which regarded the intermingled phlegm and blood stagnate as the onset factor of CHD and deficiency of health qi as the internal factor of lesions

and divided the disease progress into3 parts: phlegm accumulation

stasis and obstruction of vessel and collateral and heat-toxin amassment. With basic treatment of softening hardness and dispersing mass

Prof. RUAN treated CHD with methods such as dissipating phlegm and resolving masses

eliminating blood stasis and resolving mass and clearing heat and resolving static blood according to different stages of disease to dissipate the stasis in vessel and to keep the stable condition of atheromatous plaque.