Objective To observe the clinical efficacy of Quyu Huatan Ningxin Decoction（祛瘀化痰宁心汤） in treating angina pectoris after percutaneous coronary intervention（PCI） of patients with acute coronary syndrome.Methods A total of 90 acute coronary syndrome patients with angina after PCI were randomly divided into a control group and a treatment group

with 45 cases in each group. Both groups of patients were given standard western medicine treatment after PCI. The treatment group was orally given Quyu Huatan Ningxin Decoction on the basis of standardized treatment

1 dose per day

and both groups were treated for 8 weeks. The efficacy of angina pectoris

traditional Chinese medicine（TCM） syndrome efficacy

electrocardiography（ECG） efficacy were observed. The serum total cholesterol（TC）

triglyceride（TG）

low-density lipoprotein cholesterol（LDL-C）

and high-density lipoprotein cholesterol（HDL-C）

C-reactive protein（CRP） and safety indexes including liver function

kidney function

blood routine and urine routine were detected before and after the treatment. Results After 8 weeks of treatment

the total effective rate of angina（91. 1%）

the total effective rate of TCM syndrome（93. 3%） and the total effective rate of ECG（57. 8%） in the treatment group were significantly higher than those of the control group（respectively71. 1%

71. 1%

and 33. 3%）（P < 0. 05）. The levels of serum TC

TG

LDL-C and CRP in the treatment group were decreased more significantly than those before treatment and those of the control group after treatment（P <0. 05）. Conclusion Quyu Huatan Ningxin Decoction combined with conventional western medicine treatment can obviously relieve angina symptom of patients with acute coronary syndrome after PCI. Improving ECG performance and coronary blood flow

reducing blood lipids and inhibiting inflammation may be the main mechanism.