Objective To observe the clinical effects and safety of Yiqi Huayu Shengji Decoction（益气化瘀生肌方） in the treatment of chronic erosive gastritis with qi deficiency and blood stasis syndrome in Qinghai. Methods A total of 120 chronic erosive gastritis patients with qi deficiency and blood stasis were selected and randomly divided into a control group（57 cases） and a treatment group（63 cases）. The control group received rabeprazole entericcoated capsules

20 mg each time

once a day

and bismuth potassium citrate oral solution

5 ml each time

3 times a day. The treatment group was given modified Yiqi Huayu Shengji Decoction. The patients in both groups who were infected with Helicobacter pylori（Hp） were treated with anti-HP infection for 2 weeks. The traditional Chinese medicine（TCM） syndromes scores

endoscopic mucosal recovery socres

Hp clearance after treatment

and recurrence rate were compared. Results The total effective rate was 98. 41% in the treatment group and 87. 72% in the control group. There was significant difference between the two groups（P < 0. 05）. The TCM symptom scores and gastric mucosal scores of the both groups were decreased compared with before（P < 0. 01）

and they were decreased more in the treatment group than in the control group（P < 0. 05）. The Hp eradication rate was 100% in the treatment group

which was higher than 68. 18% in the control group（P < 0. 05）. The recurrence rate was 16. 13% in the treatment group and 46. 00% in the control group

which was lower in the treatment group than in the control group（P < 0. 01）. No significant adverse reactions were observed in either group. Conclusion Modified Yiqi Huayu Shengji Decoction has a good clinical effect in treating chronic erosive gastritis with qi deficiency and blood stasis syndrome in Qinghai. It can improve clinical symptoms

promote gastric mucosal repair

with high Hp eradication rate

low recurrence rate and good safety.