Retrospective Analysis of Clinical Efficacy of Banxia Baizhu Tianma Decoction( 半夏白术天麻汤) Combined with Atorvastatin Calcium Tablets in the Treatment of 50 Cases of Carotid Atherosclerosis with Wind Phlegm Obstructing Collateral Syndrome
CHEN Xiaomin, MING Shuping, ZHANG Teng, et al. Retrospective Analysis of Clinical Efficacy of Banxia Baizhu Tianma Decoction( 半夏白术天麻汤) Combined with Atorvastatin Calcium Tablets in the Treatment of 50 Cases of Carotid Atherosclerosis with Wind Phlegm Obstructing Collateral Syndrome[J]. Journal of Traditional Chinese Medicine2019, 60(5): 396-399.
CHEN Xiaomin, MING Shuping, ZHANG Teng, et al. Retrospective Analysis of Clinical Efficacy of Banxia Baizhu Tianma Decoction( 半夏白术天麻汤) Combined with Atorvastatin Calcium Tablets in the Treatment of 50 Cases of Carotid Atherosclerosis with Wind Phlegm Obstructing Collateral Syndrome[J]. Journal of Traditional Chinese Medicine2019, 60(5): 396-399.DOI: 10.13288/j.11-2166/r.2019.05.009.
Objective To analyze clinical efficacy of Banxia Baizhu Tianma Decoction( 半夏白术天麻汤) combined with atorvastatin calcium tablets in the treatment of carotid atherosclerosis with wind phlegm obstructing collateral syndrome. Methods Data of 100 patients of carotid atherosclerosis with wind phlegm obstructing collateral syndrome druing September 2014 to September 2017 were divided into treatment group and control group
with 50 cases in each group. The control group was given atorvastatin calcium tablets
20 mg each time
for oral administration once in the evening. The treatment group was added Banxia Baizhu Tianma Decoction
1 dose each day. Treatment course of both groups was 6 months. The carotid artery intima-media thickness( IMT)
carotid plaques in the Crouse of integral of both groups were observed before treatment
3 and 6 months after treatment. Meanwhile
serum total cholesterol( TC)
triglyceride( TG)
and low density lipoprotein cholesterin( LDL-C) were detected
and the clinical efficacy of traditional Chinese medicine( TCM) was determined after 3 and 6 months treatment. Results The clinical total effective rate in the treatment group after 3 and 6 months’ treatment was 80. 0% and 90. 0% respectively
which was higher than 64. 0% and 76. 0% in the control group. The IMT and Crouse integral of both groups after 6 months’ treatment were significantly decreased compared with before treatment( P < 0. 05). After 6 months’ treatment
the IMT and Crouse integral in the treatment group was significantly lower than those of the control group( P < 0. 05).The TC
TG
LDL-C of both groups after 3 and 6 months’ treatment were significantly lower than before treatment( P < 0. 05). The serum TC
TG
LDL-C of both groups after 6 months’ treatment were significantly lower than those after 3 months’ treatment( P < 0. 05). After 6 months’ treatment
TC
TG
LDL-C of the treatment group was significantly lower than those of the control group( P < 0. 05). Conclusion The clinical efficacy of Banxia Baizhu Tianma Decoction combined with atorvastatin calcium tablets in the treatment of carotid atherosclerosis with wind phlegm obstructing collateral syndrome was better than single use of atorvastatin calcium tablets.