LI Yingfu, XIE Xingwen, LI Ning, et al. Correlation Between Chinese Medicine Channel Ushering Theory,Signal Pathway and Bone Marrow Mesenchymal Stem Cells[J]. Journal of Traditional Chinese Medicine2019, 60(6): 477-481.
LI Yingfu, XIE Xingwen, LI Ning, et al. Correlation Between Chinese Medicine Channel Ushering Theory,Signal Pathway and Bone Marrow Mesenchymal Stem Cells[J]. Journal of Traditional Chinese Medicine2019, 60(6): 477-481.DOI: 10.13288/j.11-2166/r.2019.06.007.
Chinese medicine channel ushering theory is an important content in the theory of traditional Chinese medicine. The channel ushering drugs can guide other drugs to reach the disease location and improve the curative effect. Bone marrow mesenchymal stem cells(BMSCs) are present in the bone marrow and have a high degree of selfrenewal and self-replication ability
and can be multi-directionally differentiated. Through analyzing the relationship and transduction between bone marrow mesenchymal stem cells and PI3 K/AKT
MCP-1/CCR2
SDF-1/CXCR4
MAPK/ERK1/2
PKC signaling pathways
this paper discussed the action of promoting the migration of bone marrow mesenchymal stem cells by channel ushering drug.