The important role of hidden pathogen in the pathogenesis of henoch-schonlein purpura（ HSP） in children was expounded from the three aspects of the theoretic origin

the cause and the pathogenesis of hidden pathogen. It was believed that the hidden pathogen can be exogenous and can also be generated from the inside. The exogenous hidden pathogen can be transformed from six climatic factors

and can also occurred directly from epidemic factors

which is expressed as "the hidden pathogen in the winter

the onset of spring"and "the hidden pathogen in the summer

the onset of autumn"; The hidden pathogen of internal damage includes food damage

dampness heat

and fetal toxicity; exogenous hidden pathogen and internal damage hidden pathogen are mutual contracted

which can induce pathological pathogens

leading to a lingering disease. According to the pathogenesis of the disease

it is proposed that the clinical treatment of HSP in children should pay attention to the elimination of hidden pathogen on the basis of syndrome differentiation. Internal damage hidden pathogen are mostly treated with clearing heat and removing toxicity

clearing heat and cooling blood

clearing heat and promoting diuresis

clearing heat and eliminating food stagnation. The exogenous hidden pathogen should fully consider the exogenous hidden pathogen as the source of the disease

pay attention to the removal of external factors

and at the same time treated with dispelling wind

promoting stagnation

dispelling summer-heat

and should pay attention to prevention for recurrence based on the obvious seasonal characteristics of its repeated attack.