Objective To evaluate the clinical effects of Wenyang Yixin Therapy（温阳益心法） on coronary artery stenosis. Methods A retrospective study was conducted on 32 patients with coronary heart disease who were diagnosed by coronary angiography or coronary CT in the Chinese Medicine Clinic of China Academy of Chinese Medical Sciences from May 2010 to May 2018

using data collection and telephone interviews. The degree of coronary artery stenosis

clinical symptom score

angina pectoris and electrocardiogram

nitroglycerin reduction rate

blood pressure

blood lipids

blood glucose and safety were evaluated before and after treatment with Wenyang Yixin Therapy.Results Thirty-two patients received Wenyang Yixin Therapy for 15. 97 ± 10. 17 months on average. After treatment

the score of coronary stenosis decreased by 13. 17 ± 15. 81

and the difference was statistically significant（P <0. 05）. A total of 100 plaques occurred in 32 patients

and 56. 58% of moderate to severe plaques disappeared or decreased after treatment

and the stenosis degree decreased by（16. 45 ± 31. 25） %. The difference was statistically significant（P < 0. 01）. Symptoms such as chest pain and chest congestion basically disappeared（P < 0. 01）

with effective rate as 84. 38%. The electrocardiogram effective rate was 73. 33%

and the reduction rate of nitroglycerin was 94. 74%. After treatment

the levels of systolic blood pressure

low density lipoprotein cholesterin（LDL-C）

ratio of LDL-C to high density lipoprotein cholesterin（HDL-C） were decreased（P < 0. 05）. No liver and renal damage

adverse reactions or cardiovascular events were observed during treatment. Conclusion Wenyang Yixin Therapy can effectively reduce the degree of coronary stenosis in patients with coronary heart disease

while significantly alleviate patients’ clinical symptoms

improve myocardial ischemia and relieve angina

without significant toxin and adverse effects.