Objective To observe the effects of tongue-pharynx three-step acupuncture combined with rehabilitation training on cerebral infarction pseudo-ball paralysis and its effects on plasma endothelin-1（ET-1） and nitric oxide（NO） levels.Methods A total of 90 patients with cerebral infarction pseudo-ball paralysis were randomly divided into a tongue-pharynx three-step acupuncture combined with rehabilitation training group with 30 cases

a rehabilitation training group with 28 cases

and a tongue-pharynx three-step acupuncture group.All groups received routine treatment.On the basis of this

the tongue-pharynx three-step acupuncture combined with rehabilitation training group received rehabilitation training combined with tongue-pharynx three-step acupuncture including fan-shaped acupuncture

Jieyu three acupuncture

swift pricking blood therapy.The rehabilitation training group and the tonguepharynx three-step acupuncture group were treated with rehabilitation training and tongue-pharynx three-step acupuncture respectively

10 days as one treatment course

for continuous 2 treatment courses.The scores of water swallow test and plasma ET-1 and NO levels were measured before and after treatment in each group.The therapeutic effects of swallowing function were counted after treatment.Results The total effective rate of swallowing function in the tongue-pharynx three-step acupuncture combined with rehabilitation training group was 90.00%

that in the rehabilitation training group was 71.43%

and that in the tongue-pharynx three-step acupuncture group was 71.88%.The curative effects of the tongue-pharynx three-step acupuncture combined with rehabilitation training group were better than the rehabilitation training group and the tongue-pharynx three-step acupuncture group（P<0.05）.There was no significant difference between the rehabilitation training group and the tongue-pharynx three-step acupuncture group（P>0.05）.After treatment

the scores of water swallow test and plasma ET-1 level in each group were decreased than those in this group before treatment

and the plasma NO content was increased than that in this group before treatment（P<0.05 or P<0.01）.After treatment

the water swallow test and plasma ET-1 level of the tongue-pharynx three-step acupuncture combined with rehabilitation training group were lower than the rehabilitation training group and the tongue-pharynx three-step acupuncture group.The plasma NO content was higher than that of the rehabilitation training group and the tongue-pharynx three-step acupuncture group（P<0.05 or P<0.01）.There were no significant differences in the indexes between the rehabilitation training group and the tongue-pharynx three-step acupuncture group（P>0.05）.Conclusion Tongue-pharynx three-step acupuncture combined with rehabilitation training can effectively improve the levels of plasma ET-1 and NO in patients with cerebral infarction pseudo-ball paralysis

and has a good effect on the rehabilitation of swallowing function.