Objective To conduct a reevaluation study on systematic review/Meta-analysis of traditional Chinese medicine（TCM） treatment of myasthenia gravis（MG）

in order to evaluate the bias and the reliability of the conclusion. Methods We comprehensively searched China National Knowledge Infrastructure（CNKI）

VIP database

WanFang database

Chinese Biology Medicine（CBM）

PubMed

Embase

The Cochrane Library for literature on systematic review/Meta-analysis of TCM treatment of MG from the establishment time of databases to September 30 th

2018. The literature were evaluated in terms of methodological quality evaluation

outcome index evidence quality grading. Descriptive analysis was conducted to primary outcome index. Results A total of 7 SRs/Meta-analysis were included with 28 outcomes index. 6 papers compared the efficacy of TCM combined with western medicine between western medicine alone in treating MG. One systematic review compared the efficacy of TCM alone and western medicine alone. The AMSTAR scale score showed that there were 3 papers with a total score of 11-16

which was of medium quality. 4 papers with a total score was between 17 and 22 points

which was of high quality. GRADE grading results showed that evidences of 23 outcome index were of low or extremely low quality

and only 5 outcomes were of intermediate quality

mainly reflected in the recurrence rate

TCM syndrome scores

adverse reactions. Descriptive analysis showed that TCM treatment of MG can improve the total effective rate

reduce the clinical absolute score

clinical relative score

reduce the recurrence rate

the incidence of adverse reactions（P < 0. 05 or P < 0. 01）.Conclusion The systematic review/Meta-analysis of methodological quality of TCM treatment of MG is medium to high

but the evidence strength of the conclusion is low. The available evidence indicates that TCM combined with western medicine may have synergistic effects in the treatment of MG.