Turbid evil refers to a kind of endogenous pathological products or pathogenic factors with the characteristics of muddy

thick

viscous and cemented. Turbid evil that stagnates for a long time can transform into the toxic

it is called turbid and toxic when there appears dual features of the turbid and toxic. Turbid and toxic has the characteristics of muddy

heavy and viscous

hot

widespread

severe and obstinate

which agrees the clinical manifestation and course features of chronic kidney disease（ CKD）. The onset of CKD is hidden

turbid evil stagnates and transforms to toxic after a long term because spleen and kidney deficiency and are unable to transfer water and dampness. After turbid evil transforms into toxic

turbid and toxic can damage zang and Fu organs directly and cause various complications

commonly seen in stage 3-5 of CKD

suggesting a critical condition. Turbid and toxic has a close connection with the onset

development and prognosis of CKD. For treatment

it is suggested to use disperse surface and permeate turbidity method

aromatization of turbidity method

infiltration of turbidity and dampness method

purge the Fu organs and excrete turbidity method

the pungent opening and the bitter downward method to expel evils.