1. 广州中医药大学第一临床医学院
2. 广州中医药大学第一附属医院
3. 广州中医药大学第一临床医学院广州中医药大学第一附属医院
纸质出版:2019
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[1]黄远程,黄超原,梁怀枫,潘静琳,李培武,刘凤斌.慢性非萎缩性胃炎与慢性萎缩性胃炎证候、证素分布规律文献研究[J].中医杂志,2019,60(16):1417-1422.
HUANG Yuancheng, HUANG Chaoyuan, LIANG Huaifeng, et al. Literature Study on Distribution Rules of Syndromes and Syndrome Elements of Chronic Non-Atrophic Gastritis and Chronic Atrophic Gastritis[J]. Journal of Traditional Chinese Medicine2019, 60(16): 1417-1422.
[1]黄远程,黄超原,梁怀枫,潘静琳,李培武,刘凤斌.慢性非萎缩性胃炎与慢性萎缩性胃炎证候、证素分布规律文献研究[J].中医杂志,2019,60(16):1417-1422. DOI: 10.13288/j.11-2166/r.2019.16.015.
HUANG Yuancheng, HUANG Chaoyuan, LIANG Huaifeng, et al. Literature Study on Distribution Rules of Syndromes and Syndrome Elements of Chronic Non-Atrophic Gastritis and Chronic Atrophic Gastritis[J]. Journal of Traditional Chinese Medicine2019, 60(16): 1417-1422. DOI: 10.13288/j.11-2166/r.2019.16.015.
目的探讨慢性非萎缩性胃炎(CNAG)与慢性萎缩性胃炎(CAG)的证候、证素分布规律及差异。方法检索中国生物医学文献数据库、中国知网全文数据库、万方数据库和重庆维普中文期刊数据库
纳入有关CNAG、CAG证候的流行病学调查研究及中医临床辨证分型治疗研究。收集文献的一般资料、病例辨证分型并建立数据库
分别统计CNAG、CAG证候和病性类、病位类证素的频次、病例数以及构成比
并比较二者差异。结果共纳入文献241篇
其中CNAG文献64篇
CAG文献177篇
共计病例数36 315例
其中CNAG病例11535例
CAG病例24780例。CNAG常见证候类型依次为肝胃不和证、脾胃气虚证、脾胃湿热证、脾胃阳虚证、胃阴亏虚证、瘀阻胃络证
CAG常见证候类型依次为肝胃不和证、胃阴亏虚证、脾胃气虚证、脾胃湿热证、脾虚气滞证
其中CNAG肝胃气滞证多于CAG
CAG瘀阻胃络证多于CNAG。CNAG常见病性类证素依次为气虚、热、气滞、湿、阳虚
CAG常见病性类证素依次为气虚、热、阴虚、湿、气滞。其中CNAG气滞、阳虚证素多于CAG
CAG瘀证素多于CNAG (P <0. 05)。CNAG和CAG病位均以胃、脾、肝、肠为主
其中CNAG病位多在胃
CAG病位多在脾(P <0. 05)。结论肝胃不和证和脾胃气虚证为CNAG和CAG的核心证候
其中CNAG病机以胃气滞为显著
CAG病机以脾气虚更为显著。胃阴亏虚、胃络瘀阻是CAG区别于CNAG的主要证候特点。
Objective To explore the distribution rules and differences of syndromes and syndrome elements of chronic non-atrophic gastritis( CNAG) and chronic atrophic gastritis( CAG). Methods By searching Chinese Biomedical database( CBM)
Chinese National Knowledge Infrastructure( CNKI)
Wanfang database and VIP database
the epidemiological investigations on CNAG and CAG syndromes and study on clinical syndrome differentiation and treatment of traditional Chinese medicine( TCM) were included. The general information of the literature
case syndrome differentiation were collect to establish a database. The frequency
number of cases and composition ratio of CNAG
CAG syndrome and disease type
disease type syndrome elements were calculated to compare the differences.Results A total of 241 articles were collected
including 64 articles of CNAG and 177 articles of CAG
with a total of 36 315 cases
among which 11 535 were CNAG cases and 24 780 were CAG cases. The frequent syndromes of CNAG were disharmony of the liver and the stomach
qi deficiency of the spleen and the stomach
heat and dampness of the spleen and the stomach
yang deficiency of the spleen and the stomach
yin deficiency of the stomach
bloods stasis obstructing the stomach collaterals. The frequent syndromes of CAG were disharmony of the liver and the stomach
yin deficiency of the stomach
qi deficiency of the spleen and the stomach
heat and dampness of the spleen and the stomach
spleen deficiency and qi stagnation. The number of qi stagnation in the liver and stomach of CNAG was larger than that of CAG
while the number of bloods stasis obstructing the stomach collaterals of the CAG was larger than that of CNAG. The frequent syndrome elements of disease type of CNAG were qi deficiency
heat
qi stagnation
dampness
yang deficiency. The frequent syndrome elements of disease type of CAG were qi deficiency
heat
yin deficiency
dampness
qi stagnation. The number of syndrome elements of qi stagnation and yang deficiency of CNAG was larger than that of CAG
and the blood stasis of CAG was more than that of CNAG( P < 0. 05). The location of CNAG and CAG were mainly in the stomach
spleen
liver and the intestines
in which CNAG was mainly located in the stomach
and CAG was mainly in the spleen( P < 0. 05). Conclusions Disharmony of the liver and the stomach and qi deficiency of the spleen and the stomach are the core syndrome of CNAG and CAG
among which the stomach qi stagnation is significant in CNAG and the spleen qi deficiency is significant in CAG. The stomach yin deficiency and the blood stasis obstructing the stomach collaterals are the main syndrome characteristics differentiating CAG and CNAG.
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