This paper summarized WANG Xisheng’e experience in treating malignant tumors based on syndrome differentiation with principles of "supporting

resolving

consolidating

regulating"

based on his understanding of pathogenesis of malignant tumors such as "deficiency

stasis

mass

toxin". "Supporting"means supporting healthy qi

and cultivating root sources; "Resolving"covers activing blood to resolve stasis

resolving phlegm to eliminate dampness

softening hard and dissipating mass

clearing heat to remove toxin; "Consolidating"means nourishing stomach qi

and improving stomach function; "Regulating"means regulating qi and blood

balancing yin and yang

regulating zang-fu organs and emotions. Clinical treatment should be rooted in invigorating the spleen

tonifying the kidney

supporting the healthy qi and anti-tumor. Self-made prescription modified Jianpi Bushen Decoction（ 健脾补肾汤） was commonly used for treatment.