1. 河南中医药大学呼吸疾病诊疗与新药研发河南省协同创新中心/河南省中医药防治呼吸病重点实验室
2. 河南中医药大学第一附属医院
纸质出版:2019
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[1]李建生,余学庆.慢性阻塞性肺疾病中医分期分级防治策略[J].中医杂志,2019,60(22):1895-1899.
LI Jiansheng, YU Xueqing. Strategy of Traditional Chinese Medicine Prevention and Treatment of Chronic Obstructive Pulmonary Disease Based on Classification of Stages and Grades[J]. Journal of Traditional Chinese Medicine2019, 60(22): 1895-1899.
[1]李建生,余学庆.慢性阻塞性肺疾病中医分期分级防治策略[J].中医杂志,2019,60(22):1895-1899. DOI: 10.13288/j.11-2166/r.2019.22.002.
LI Jiansheng, YU Xueqing. Strategy of Traditional Chinese Medicine Prevention and Treatment of Chronic Obstructive Pulmonary Disease Based on Classification of Stages and Grades[J]. Journal of Traditional Chinese Medicine2019, 60(22): 1895-1899. DOI: 10.13288/j.11-2166/r.2019.22.002.
慢性阻塞性肺疾病(COPD)的演变呈渐进式过程
围绕COPD不同阶段疾病特点和关键环节
采取分期、分级的防治策略与方法
可充分发挥中医药优势并提高临床疗效。在系统分析COPD分期、分级的临床特征与防治目标及中医病机与证候规律的基础上
提出中医药防治COPD分期、分级的防治策略与目标。1)根据疾病分期:稳定期的防治策略与目标是缓解症状、预防疾病进展、降低急性加重发生的风险
治疗应以"缓则治其本"为原则
法宜扶正(补肺、健脾、益肾)为主
佐以化痰、活血;急性加重期重在使本次急性加重的影响最小化、减轻临床症状、降低死亡风险
治疗应遵"急则治其标"原则
法宜清化宣降为主
包括清热化痰、燥湿化痰、温化寒饮、活血化瘀、宣降肺气等;急性加重危险窗期重在防止再次急性加重的发生、促进恢复进入稳定期
治疗当祛邪(化痰、活血)扶正(补益肺气、补肺健脾、补益肺肾等)并重。2)根据肺功能(气流受限严重程度)分级:GOLD 1、2级COPD患者重在保护肺功能、延缓疾病进展
治疗以扶正(补肺、健脾辅以益肾)为主
佐以化痰、活血; GOLD 3、4级患者重在减少急性加重、提高生存质量
治疗宜扶正(补肺、益肾辅以健脾)为主
佐以化痰、活血;晚期患者应注重合并疾病的防治、降低死亡风险、提高生存质量
尤其要注意降低慢性呼吸衰竭病死率
治疗应以益气、活血、化痰为主。
The evolution of chronic obstructive pulmonary disease(COPD) is a gradual process. Focusing on the characteristics and key links of different stages of COPD
adopting staged grading prevention strategies and methods is of great practical significance for giving full play to the advantages of traditional Chinese medicine(TCM) and improving clinical efficacy. Based on the systematic analysis of the clinical characteristics
prevention and treatment goals of COPD
and the pathogenesis and syndromes
this paper put forward the prevention and treatment strategies and goals of TCM prevention and treatment of COPD:(1) According to the stage of the disease: the prevention and treatment strategy and goal of the stable period is to relieve symptoms
prevent disease progression
and reduce the risk of acute exacerbation. The treatment should follow the principle of "treating the root causes for slow onset"
and the methods should be enforcing healthy qi(tonifying the lung
invigorating the spleen
benefiting the kidney)
accompanied by resolving phlegm and improving blood circulation. For the acute exacerbation period
it is to minimize the impact of this acute exacerbation
reduce clinical symptoms
and reduce the risk of death. The treatment should follow the principle of "treating the symptoms for acute onset"
and the methods should be clearing
resolving
ventilating
and descending
including clearing heat and resolving phlegm
drying dampness and resolving phlegm
warming and resolving cold fluids
promoting blood circulation and removing blood stasis
and ventilating and descending lung qi.For the critical window of acute exacerbation
it is to prevent the occurrence of acute exacerbation and promote recovery into a stable period. The treatment should both eliminate pathogens(resolving phlegm and promoting blood circulation) and enforce healthy qi(tonifying and benefiting lung qi
replenishing the lung and strengthening the spleen
replenishing the lung and kidney
etc.).(2) According to the function of lung function(severity of airflow limitation) : for COPD patients with Global Initiative for Chronic Obstructive Lung Disease(GOLD) level 1 and 2
the treatment should protect against the decrease of lung function and delay the progression of the disease. The treatment is based on enforcing the healthy qi(reinforcing the lung
invigorating the spleen
and replenishing the kidney)
accompanied with resolving phlegm and promoting blood circulation; for patients of GOLD level 3 and 4
should focus on reducing acute exacerbation
improving quality of life
and the treatment should enforce the healthy qi(reinforcing the lung
benefiting the kidney
and invigorating the spleen)
accompanied by resolving phlegm and promoting blood circulation; for advanced patients
should pay attention to the prevention and treatment of combined diseases
reduce the risk of death
improve the quality of life
especially pay attention to reducing the mortality rate of chronic respiratory failure
and the treatment should be based on replenishing vital energy
promoting blood circulation
and removing phlegm.
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