Syndrome differentiation and treatment（SDT） is the main method of traditiaonl Chinese medicine（TCM） diagnosis and treatment of disease

and individualized diagnosis and treatment is its outstanding feature. The issue of evaluation of therapeutic efficacy of SDT has long been a bottleneck restricting the development of TCM. By integrating the characteristics of modern clinical epidemiology

evidence-based medicine and SDT and adhering to the clinical principle that the key contribution factors for effectiveness of SDT are not prescriptions but physicians

with further referring to the evaluation idea in competitive sports for athletes to control the equipment skills

we proposed an idea and approach to evaluate the effectiveness of SDT by changing the evaluation objects from drugs to physicians who prescribe the drugs. The evaluation process should also adhere to the basic principle of "control". The appropriate clinical design should be adopted such as random control and cohort study

and the real world "full sample

mixed big data" and "sampling

accurate small data" were combined. Methods were selected accoding to clinical purpose. The evaluation results firstly recommend the appropriate "medical doctor" to treat a certain disease

rather than a certain "prescription". The comprehensive efficacy of "representative team" was used to reflect the therapeutic effect of TCM treatment of a certain disease within a certain range. The research ideas

strategies and methods break through the stereotype of traditional clinical evaluation and open up a new way for individualized clinical evaluation of TCM.