The theory of traditional Chinese medicine（TCM） properties is an important part of the basic theory of TCM

but there is a lack of scientific clinical research methods in the research on the theory. After thousands of years of practice

Chinese physicians in past dynasties have formed a set of derivation methods of TCM properties

based on clinical efficacy and syndrome treatment. However

due to the impact of modern medicine and the limitations of this method

the development of these methods has stagnated. This article introduced the clinical efficacy derivation method and its characteristics in TCM properties of clinical research

summarizing the value of traditional clinical efficacy derivation method in current research on TCM properties

combing the requirements of modern scientific research

and condensing the key points of efficacy derivation method needing to be improved. It is hoped to provide ideas for establishing traditional and modern Chinese medicine clinical research methods.