Since the outbreak of COVID-19

70 relevant clinical trials have been registered in Chinese Clinical Trial Register

ClinicalTrials.gov and Clinical Trial Registration Platform of China Center for Evidence-based Medicine of Traditional Chinese Medicine

focusing on multiple fields including disease screening

diagnosis

prevention

treatment

prognosis and rehabilitation. But at the same time

it also exposed some problems

such as research competing for clinical resources

large difference in major indicators without clear research objectives

difficult for comparison on results

lack of basis for setting sample

confusion in basic concepts

clinical study design requiring improvement. In order to enhance the ability to respond to public health emergencies

this paper proposes a strategy to promote establishment of clinical trial collaboration and sharing mechanism

and also puts forward relevant suggestions from four aspects including promoting information sharing on clinical trials

strengthening the overall supervision on clinical trials

improving the emergency response mechanism of clinical trials and organizing high-level team for clinical trials.