1. 中国中医科学院广安门医院
2. 中国中医科学院中医临床基础医学研究所
纸质出版:2020
移动端阅览
[1]李延婷,姜泉,巩勋,李克嵩,刘蔚翔,翟争,刘岩.类风湿关节炎患者中医药治疗现状调查分析[J].中医杂志,2020,61(08):676-680.
LI Yanting, JIANG Quan, Gong Xun, et al. Status Investigation and Analysis on Traditional Chinese Medicine Treatment in Rheumatoid Arthritis Patients[J]. Journal of Traditional Chinese Medicine2020, 61(8): 676-680.
[1]李延婷,姜泉,巩勋,李克嵩,刘蔚翔,翟争,刘岩.类风湿关节炎患者中医药治疗现状调查分析[J].中医杂志,2020,61(08):676-680. DOI: 10.13288/j.11-2166/r.2020.08.008.
LI Yanting, JIANG Quan, Gong Xun, et al. Status Investigation and Analysis on Traditional Chinese Medicine Treatment in Rheumatoid Arthritis Patients[J]. Journal of Traditional Chinese Medicine2020, 61(8): 676-680. DOI: 10.13288/j.11-2166/r.2020.08.008.
目的了解接受中医药治疗的类风湿关节炎(RA)患者就医及治疗现状。方法收集类风湿关节炎中医数据中心(CRDC-TCM)中多家中医院和部分西医院采用中医药治疗的RA患者病例信息
采用描述统计方法分析患者的疾病活动度(DAS28)[分别以血沉(ESR)、C-反应蛋白(CRP)计算]、病程、系统性受累和用药情况。结果共纳入RA患者1247例
其中男性205例(16.4%)
女性1042例(83.6%)。患者平均疾病活动度DAS28-ESR(5.50±1.45)分
中、高疾病活动度患者1175例(96.4%);患者平均疾病活动度DAS28-CRP(4.80±1.40)分
中、高疾病活动度患者1096例(92.9%)。患者中位病程为6(2
12)年
其中病程1<病程≤5年的患者最多
共578例(46.4%)。无系统受累者956例(76.7%)
有系统受累者291例(23.3%)
消化系统受累最常见
共186例(14.9%)
其次为血液系统受累88例(7.1%)、呼吸系统受累82例(6.6%)。患者双手X线分期以Ⅱ、Ⅲ期居多
分别为199例(37.1%)
154例(28.7%)。895例(71.8%)患者服用过或正在服用非甾体类消炎药(NSAIDs)
835例(67.0%)患者服用过或正在服用抗风湿药物(DMARDs)
679例(54.5%)患者服用过或正在服用中成药和中药提取制剂
674例(54.0%)患者服用过或正在服用汤剂
256例(20.5%)患者使用过或正在使用中药外用药。结论采用中医药治疗的RA患者病情以中、重度较多
部分存在系统损害。在治疗方面
DMARDs、NSAIDs是主要选择用药
中药汤剂、中成药及中药提取制剂均发挥着重要的作用。
Objective To understand current status of patients with rheumatoid arthritis(RA) receiving traditional Chinese medicine(TCM) treatment. Methods Case information of RA patients treated with TCM in many TCM hospitals and some western medicine hospitals was collected from Chinese Rheumatoid Arthritis Data Center-Traditional Chinese Medicine(CRDC-TCM). Disease activity scores(DAS28) calculated by erythrocyte sedimentation rate(ESR) and C-reactive protein(CRP) respectively
course of disease
systemic involvement and medication in patients were analyzed by using descriptive statistical methods. Results A total of 1247 RA patients were included
with 205 males(16.4%) and 1042 females(83.6%). The average DAS28-ESR was(5.50±1.45) points
and 1175 patients(96.4%) were with moderate and high disease activity scores. The average DAS28-CRP was(4.80±1.40) points
and there were 1096 patients(92.9%) with moderate and high disease activity scores. The median course of disease was 6(2
12) years
578(46.4%) patients with a course of more than 1 year and no more than 5 years. There were 956 cases(76.7%) without systemic involvement
and 291 cases(23.3%) with systemic involvement. Among them
digestive system involvement was the most common
with 186 cases(14.9%)
followed by 88 cases with blood system involvement(7.1%) and 82 cases with respiratory system involvement(6.6%). X-ray staging of patients′ hands was mostly in stage Ⅱ and Ⅲ
with 199 cases(37.1%) and 154 cases(28.7%)
respectively. A total of 895(71.8%) patients had taken or were taking non-steroidal anti-inflammatory drugs(NSAIDs)
835(67.0%) patients had taken or were taking disease-modified anti-rheumatic drugs(DMARDs)
679(54.5%) patients had taken or were taking Chinese patent medicine and extract preparations of Chinese materia medica
674(54.0%) patients had taken or were taking decoctions
and 256(20.5%) patients had used or were using external applied agent of Chinese materia medica. Conclusion Status in most RA patients treated with TCM is moderate and severe
and some of them have systemic damage. In terms of treatment
DMARDs and NSAIDs are main drugs of choice. Chinese medicine decoction
Chinese patent medicines and extract preparations play an important role.
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