Objective To observe the effect of Jideshu Ointment Formula（脊得舒膏方） on rehabilitation after total hip arthroplasty（THA） for ankylosing spondylitis（AS） patients with hip ankylosis of liver and kidney deficiency syndrome. Methods A total of 48 patients were randomly divided into a treatment group and a control group with 24 in each group. The control group was treated with routine treatment after THA; the treatment group was treated with Jideshu Ointment Formula on the basis of the control group for one month. Erythrocyte sedimentation rate（ESR）

C-reactive protein（CRP）

Harris score of hip joint

range of motion（ROM）

visual analogue scale（VAS）

traditional Chinese medicine（TCM） syndrome score

and quality of life score were compared and observed before and 1

3

6

12 months after operation

to evaluate the curative effects of TCM syndromes and the safety. Results After 12 months of the surgery

the ESR

CRP

Harris scores

hip joint ROM

VAS and SF36 scores including physiological function（PF）

physiological function（RP）

physical pain（BP）

general health status（GH）

energy（VT）

emotional function（RE）

social function（SF）

mental health（MH） were significantly improved. VAS of the treatment group was significantly lower than that of the control group at the 3 rd and 6 th month after operation（P<0.05）; 12 months after the surgery

the curative effects of TCM syndrome in the treatment group was significant（79.17%）

which was supperior to that in the control group（33.33%）; 12 months after the surgery

SF scores of all dimensions of the treatment group was supperior to that of the control group（P<0.05）. There was no significant abnormal change of liver and kidney functions and no adverse drug reactions in both groups after treatment. Conclusion Modifed Jideshu Ointment Formula has obvious advantages in reducing pain

improving curative effect and improving the quality of life of patients with AS hip joint ankylosis and liver kidney deficiency after THA.