Given the real world comparative effectiveness research（CER） method has been widely used abroad in the field of medicine and health

medical information technology has been popularized

large clinical database technology develops and has been applied in our country

those provide an effective way to get real world clinical data of traditional Chinese medicine（TCM）

and provide powerful conditions for large-scale development of real world Chinese medicine injection CER. The use of clinical medical big data to develop real world Chinese medicine injection CER is conducive to comprehensive

multi-angle and multi-level clinical evaluation from individual to the whole

which is consistent with the overall view of TCM and the thinking of syndrome differentiation and treatment. Based on this

it is proposed to integrate multiple hospital information management system data to build a real world database that conforms to the research of multi-source heterogeneous data

unified structure

and data specifications

to conduct in-depth mining

to select clinical efficacy evaluation indicators that meet the TCM characteristics

and to develop TCM injections CER in the real world

which provides ideas for TCM efficacy evaluation studies in line with TCM characteristics.