Objective To investigate and analyze the clinical characteristics and distribution rules of traditional Chinese medicine（TCM） syndromes of patients with coronavirus disease 2019（COVID-19） in Henan Province

in order to provide a basis for further optimizing the plan of TCM syndrome differentiation and treatment of COVID-19. Methods Based on literature analysis

combined with expert opinion

the "Henan Province COVID-19 Clinical Survey Form" was formulated. A total of 524 cases of patients with COVID-19 were collected as the general data

clinical symptoms

tongue and pulse

etc.

and dialectical analysis was conducted to explore distribution of TCM syndromes of patients in different age groups（≤45 years old

46-60 years old

>60 years old） and different clinical types（mild or common

serious

critical type）. Results Among the 524 patients

304 were male and 220 were female; 349 were mild or common type

144 were serious type

and 31 were severe type; the median age was 45（33

55） years; the median duration of symptoms was 10（6

15）days. The patient′s main clinical symptoms（percentage >20%） include fever

chills

fatigue

dyspnea

shortness of breath

wheezing

and dyspnea. The tongue coating is mainly greasy（175 times）

white coating（149 times） and yellow coating（127 times）. The tongue quality is common pale tongue（170 times） and red tongue（151 times）. Pulse manifestations are mainly rapid pulse（112 times） and slippery pulse（100 times）. TCM syndromes mainly include cold dampness obstructed in lung syndrome（119 cases

22.71%）

damp heat stagnated in lung syndrome（113 cases

21.56%）

epidemic toxin blocking in lung syndrome（76 cases

14.50%）

dampness obstructing lung and stomach syndrome（70 Cases

13.36%）

dampness obstructing lung defense syndrome（63 cases

12.02%）. There was no statistically significant difference in the distribution of TCM syndromes among patients of all ages（P>0.05）. The distribution of cold dampness obstructing lung syndrome

dampness and heat stagnating in lung syndrome

epidemic toxin blocking lung syndrome

dampness obstructing lung and stomach syndrome

dampness obstructing lung defense syndrome

inner blocking causing collapse syndrome in different clinical types are statistically significant（P<0.01）. Conclusion The patients with COVID-19 in Henan Province are mostly young and middle-aged

and the main types are common and severe; the TCM syndromes are cold dampness obstructed in lung syndrome

damp heat accumulating in lung syndrome

epidemic toxin blocking lung syndrome and dampness obstructed in lung defense syndrome.