In the face of increasing emphasis on medical research in the real world

narrative medicine from the perspective of qualitative methodology has received great attention

and there has been a development trend of integration with evidence-based medicine. This paper discusses on the 3 questions of the integration of evidence-based medicine and narrative medicine. Based on the literature review

we analyzed clinical research and its application from the perspective of quantitative methodology

emphasizing that the golden rules of traditional clinical research have limitations; guidelines based on traditional clinical research have also some limitations; doctors′ decision-making thinking is affected by many factors. We further explain the concept and basic types of narrative medicine from the perspective of qualitative methodology

and reflect on the integration of evidence-based medicine and narrative medicine from the perspective of mixed method research

emphasizing that real-world evidence can be incorporated into the effective evidence provided by both evidence-based medicine and narrative medicine

which together deepen the understanding of diseases and patients

and promote the development of medicine.