This paper discusses the design and implementation methods used in interview questions when conducting researches about the inheritance of famous Chinese medicine doctors′ experience. The methods should be chosen appropriately considering the research purpose. The basic information of the target population should be well understood. The starting questions of the interview is the basis to construct a mutual belief between the interviewer and the interviewee. When designing the interview questions

it is necessary to closely follow the research purpose

flexibly use either open-ended

closed-ended

clear

concrete or abstract questions

and appropriately set the questions regarding different target population. When necessary

it is suggested to ask further questions after the target questions for more information. Open-ended questions are recommended at the end of the interview. The pre-interview and expert consensus meeting can be used to optimize the interview checklist. The familiarity of the interview methods will help improving the efficiency and quality of an interview

enabling sufficient breadth and depth of exploration and thus promoting the efficient inheritance of famous Chinese medicine doctors′ experience.