Objective To explore the distribution of traditional Chinese medicine（TCM） pattens of tachyarrhythmia

and the composition rule of Chinese herbal medicine（CHM） for treatment of tachyarrhythmia

based on data mining technologies. Methods Electronic databases including CNKI

VIP

and Wanfang were searched from the inception date till June 1 st

2020

for clinical observational studies and randomized control trials assessing CHM for tachyarrhythmia. Data on TCM pattens

patten elements

frequency of herbs

and herbal functions were collected. Association rule mining and systematic clustering analysis were performed for the high-frequency herbs. Results Totally

127 studies involving 5684 participants were included. Twenty-one TCM pattens were covered

and the three most common pattens were qi-yin deficiency with stasis patten（1009）

qi and yin deficiency patten（984）

and heart yang depletion patten（662）. Nine patten elements related to nature of disease were found

of which qi deficiency（3347）

yin deficiency（2441）

and blood stasis（2330） were the top three in frequency. There were five patten elements found to be related to disease location. One hundred and thirty-two recipes involving 110 herbs were used

of which Gancao（Radix et Rhizoma Glycyrrhizae）（71） was the most frequently used herb

followed by Danshen（Radix et Rhizoma Salviae Miltiorrhizae）（64）

Maidong（Radix Ophiopogonis）（58）

Wuweizi（Fructus Schisandrae Chinensis）（48）

and Dangshen（Radix Codonopsis）（41）. Association analysis of 30 high-frequency herbs showed that Wuweizi-Gancao

Danshen-Gancao

Wuweizi-Maidong were the top three herbal pairs of highest degree of support; in terms of the degree of confidence

Maidong-Shengdihuang（Radix Rehmanniae Recens）

Muli（Concha Ostreae）-Longgu（Os Draconis）

Gancao-Longgu were the top three highest. Through clustering analysis

30 high-frequency herbs were grouped into 11 clusters. Conclusion Deficiency-excess complex is the main pathogenesis of tachyarrhythmia

which is mainly manifested as qi-yin deficiency and stasis patten. Deficiency patten elements

mainly as qi deficiency and yin deficiency

were more relevant to the nature of disease than excess patten elements such as blood stasis. The basic treatment methods for tachyarrhythmia are boosting qi and nourishing yin

invigorating blood and dissolving stasis

as well as calming the mind and relieving fright. If necessary

methods of warming yang and supplementing blood

rectifying qi and dissolving phlegm

clearing heat and cooling the blood can be added to.