Objective To investigate the risk factors related to hypertension complicated with stroke

and to initially construct a risk prediction model for hypertension complicated with stroke. Methods Through Tianjin Community Health Service System（HIS）

data were retrospectively collected from 3859 hypertension patients who established the medical file in the Beichen District Community Health Service Center of Tianjin from January 1 st

2018 to December 31 st

2019 with complete data preservation. According to whether there was complication of stroke

the included patients were divided into stroke group（412 cases

10.68%） and non-stroke group（3447 cases

89.32%）. Univariate and multivariate analysis were used to figure out the high-risk factors of hypertension complicated with stroke and further establish a predictive model. The Hosmer-Lemeshow goodness-of-fit test and receiver operating characteristic curve（ROC） were used to evaluate the predictive model. Results The univariate analysis showed that the white blood cell count

neutrophil percentage

lymphocyte percentage

fasting blood glucose

total bilirubin

blood creatinine

blood urea nitrogen

total cholesterol

triglycerides

low density lipoprotein cholesterol

high density lipoprotein cholesterol

age

sex

smoking history

meat and vegetable balanced and salty diet

meat-based salty diet

vegetarian-based salty diet

and qi deficiency were potential risk factors for hypertension complicated with stroke. The multivariate analysis showed that total cholesterol

low-density lipoprotein cholesterol

body mass index（BMI）

and meat-based salty diet were independent risk factors for hypertension complicated with stroke. The predictive model was established as follow: Logit（P）=1.580-0.610×total cholesterol+0.525×low-density lipoprotein cholesterol-0.075×BMI+2.064×meat-based salty food（1 represented yes

0 represented no）

with diagnostic sensitivity of 66.20%

specificity of 54.70%

and the agreement rate of 74.76%. Conclusion Total cholesterol

low-density lipoprotein cholesterol

BMI

and meat-based salty diet are considered to be the high-risk factors for hypertension complicated with stroke

and the risk prediction model established on these factors is found to be in good agreement with the clinical diagnosis

and can be used to quantitatively assess the risk of stroke in patients with hypertension.