MA Rong,CHEN Hanjiang,ZHANG Xilian,et al.Pathogenesis of Fetal Epilepsy from “Nature Changes of the Endowment, Inability of Essence to Transform into Qi”[J].Journal of Traditional Chinese Medicine,2022,63(11):1009-1012.
MA Rong,CHEN Hanjiang,ZHANG Xilian,et al.Pathogenesis of Fetal Epilepsy from “Nature Changes of the Endowment, Inability of Essence to Transform into Qi”[J].Journal of Traditional Chinese Medicine,2022,63(11):1009-1012.DOI: 10.13288/j.11-2166/r.2022.11.003.
Early infantile epileptic encephalopathy (EIEE) is consistent with fetal epilepsy in the ancient medical books, and has the characteristics of “nature changes”. Considering the internal relationship between nature changes and endowment, essence and
qi
, it is proposed that the core pathogenesis of EIEE is nature changes of the endowment and the inability of essence to transform into
qi
, mainly manifested as “insufficiency of quantity” and “change of quality” of kidney essence. Careless pregnancy and original
qi
impairment are important pathogenic factors, while unbalanced
qi
in the five
zang
(脏),
qi
transformation disorder, and phlegm
qi
counterflow are the beginning of the disease. For treatment, it is suggested to mainly supplement kidney and bank up the original
qi
, take dynamic syndrome differentiation, and use the method of fortifying the spleen, softening the liver, clearing up phlegm and extinguishing wind in supplementation.
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references
PENNELL PB . Unravelling the heterogeneity of epilepsy for optimal individualised treatment: advances in 2019 [J]. Lancet Neurol , 2020 , 19 ( 1 ): 8 - 10 .