中国中医科学院广安门医院,北京市西城区北线阁5号,100053
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收稿:2022-08-24,
修回:2022-12-27,
纸质出版:2023-04-17
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布天杰,杨亚男,史佩玉等.从代谢重编程探讨甲状腺功能亢进症阴虚阳亢、气滞痰阻证的病机实质[J].中医杂志,2023,64(08):779-783.
BU Tianjie,YANG Yanan,SHI Peiyu,et al.Exploring the Pathogenesis of Hyperthyroidism with Syndromes of Yin Deficiency and Yang Hyperactivity, Qi Stagnation and Phlegm Obstruction from the Perspective of Metabolic Reprogramming[J].Journal of Traditional Chinese Medicine,2023,64(08):779-783.
布天杰,杨亚男,史佩玉等.从代谢重编程探讨甲状腺功能亢进症阴虚阳亢、气滞痰阻证的病机实质[J].中医杂志,2023,64(08):779-783. DOI: 10.13288/j.11-2166/r.2023.08.006.
BU Tianjie,YANG Yanan,SHI Peiyu,et al.Exploring the Pathogenesis of Hyperthyroidism with Syndromes of Yin Deficiency and Yang Hyperactivity, Qi Stagnation and Phlegm Obstruction from the Perspective of Metabolic Reprogramming[J].Journal of Traditional Chinese Medicine,2023,64(08):779-783. DOI: 10.13288/j.11-2166/r.2023.08.006.
以代谢重编程作为切入点,探讨甲状腺功能亢进症阴虚阳亢、气滞痰阻证的病机实质。认为代谢重编程以能量流向紊乱、代谢过程转变、系统功能障碍为特点,贯穿于甲状腺功能亢进症的发生发展过程,其引发的营养物质供能失常、免疫炎症等内分泌代谢功能紊乱与阴虚阳亢、气滞痰阻证的病机本质趋同,且表征相仿。滋阴潜阳、理气化痰治法能够纠正体内能量与物质代谢失稳的状态,调节各系统的生理功能,逆转代谢重编程以达到治疗甲状腺功能亢进症的目的。
This paper discussed the pathogenesis of hyperthyroidism with syndromes of
yin
deficiency and
yang
hyperactivity,
qi
stagnation and phlegm obstruction from ther perspective of metabolic reprogramming. It is believed that metabolic reprogramming is characterized by energy flow disorder, metabolic process transformation, and system dysfunction, and runs throughout the whole process of hyperthyroidism from its occurrence to the development. The induced endocrine and metabolic disorders, such as abnormal energy supply of nutrients and immune inflammation, are similar to the pathogenesis of
yin
deficiency and
yang
hyperactivity,
qi
stagnation and phlegm obstruction syndromes in the nature, having similar symptoms. The method of enriching
yin
and subduing
yang
, rectifying
qi
and dissolving phlegm can be used to treat hyperthyroidism as it can correct the unstable state of energy and substance meta-bolism in the body, regulate the physiological functions of various systems, and reverse metabolic reprogramming.
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