中国中医科学院广安门医院,北京市西城区北线阁5号,100053
drjieli2007@126.com
收稿:2022-12-12,
修回:2023-01-30,
纸质出版:2023-07-17
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马心怡,曹璐畅,朱潇雨等.基于五观辨治体系从瘀毒论治放射性肺损伤[J].中医杂志,2023,64(14):1431-1435.
MA Xinyi,CAO Luchang,ZHU Xiaoyu,et al.Treatment of Radiation-induced Lung Injury from Stasis Toxin based on Five Views on Differentiation and Treatment[J].Journal of Traditional Chinese Medicine,2023,64(14):1431-1435.
马心怡,曹璐畅,朱潇雨等.基于五观辨治体系从瘀毒论治放射性肺损伤[J].中医杂志,2023,64(14):1431-1435. DOI: 10.13288/j.11-2166/r.2023.14.004.
MA Xinyi,CAO Luchang,ZHU Xiaoyu,et al.Treatment of Radiation-induced Lung Injury from Stasis Toxin based on Five Views on Differentiation and Treatment[J].Journal of Traditional Chinese Medicine,2023,64(14):1431-1435. DOI: 10.13288/j.11-2166/r.2023.14.004.
放射性肺损伤是恶性肿瘤放疗后的常见并发症,中医学认为热毒津亏、血脉瘀滞是放射性肺损伤常见病机,“瘀毒”是其重要病理因素。围绕“瘀毒”与放射性肺损伤的关系,结合五观辨治模式,提出以“时空观”察疾病的动态发展过程,“核心观”论不同阶段的关键病机,并提出截癌毒、清热毒、化瘀毒三大治法,以“症状观”缓解突出症状,以“精准观”探讨中医治疗的优势靶点,在“未病观”下从未病先防、已病防变、瘥后防复三个方面防治放射性肺损伤。从全周期防治的角度为放射性肺损伤的临床治疗提供参考。
Radiation-induced lung injury (RILI) is a common complication after radiotherapy for malignant tumors. In traditional Chinese medicine (TCM), heat toxin with fluid depletion, and blood vessels stasis is a common pathogenesis of RILI, and “stasis” and “toxin” are important pathological factors. Focusing on the relationship between the theory of “stasis toxin” and RILI, considering the five views on differentiation and treatment model, this paper proposed to investigate the dynamic development process of the disease from the “space-time view”, discuss the key disease mechanisms at different stages from the “core view”, alleviate the prominent symptoms from the “symptom view”, and put forward the three treatment methods of cutting off cancer toxin, clearing heat toxin and dissolving stasis. It is advised to relieve prominent symptoms from “symptom view”, explore the advantageous targets of TCM treatment from the “precise concept”, and prevent and treat RILI from the “preventing disease before it arises”, “controlling the development of existing disease” and “avoiding recurrence after recovery”. This paper aims to provide ideas in terms of full-cycle prevention and treatment of RILI and provide more valuable clinical reference.
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