YU Yunfeng,HU Gang,ZHOU Manli,et al.Differentiation and Treatment of Bipolar Disorder based on Qi, Phlegm, Fire and Deficiency[J].Journal of Traditional Chinese Medicine,2023,64(19):2037-2040.
YU Yunfeng,HU Gang,ZHOU Manli,et al.Differentiation and Treatment of Bipolar Disorder based on Qi, Phlegm, Fire and Deficiency[J].Journal of Traditional Chinese Medicine,2023,64(19):2037-2040.DOI: 10.13288/j.11-2166/r.2023.19.016.
Bipolar disorder (BD) is considered to be mainly related to
qi
, phlegm, fire and deficiency. Binding constraint of liver
qi
is the initial cause, while phlegm and
qi
interact obstruction as well as phlegm and fire interact binding is the key pathogenesis of the transformation between depression and mania, and deficiency of both
qi
and
yin
is the main reason of the protracted course of disease. In clinical practice, BD is divided into binding constraint of liver
qi
pattern, phlegm and
qi
interact obstruction pattern, phlegm and fire interact binding pattern, and deficiency of both
qi
and
yin
pattern, which can be treated with
Jinyu Shugan Powder
(金玉疏肝散),
Kaiyu Wendan Decoction
(开郁温胆汤),
Qingxin Huatan Decoction
(清心化痰汤), and
Baihe Shengmai Beverage
(百合生脉饮) in their modifications respectively; moreover, Guanye Jinsitao (
Herba Hyperici Perforati
) is usually used to rectify
qi
, relieve phlegm and clear heat. It is also suggested to put focus on the prevention and treatment of
qi
, phlegm and heat simultaneously, and modify the medicinals flexibly in accordance with the pathogenesis evolution and the abnormal exuberance.
关键词
Keywords
references
GRANDE I , BERK M , BIRMAHER B , et al . Bipolar disorder [J]. Lancet , 2016 , 387 ( 10027 ): 1561 - 1572 .
CARVALHO AF , FIRTH J , VIETA E . Bipolar disorder [J]. N Engl J Med , 2020 , 383 ( 1 ): 58 - 66 .