Based on the theory of

ti

（character， 体） and

yong

（function， 用） in mental illness， ZHAO Yonghou's clinical experience in staged differentiation and treatment of schizophrenia is summarized. According to the theory， the core disease location of schizophrenia is in the brain， which is closely related to the organs，

qi

， and blood. It is proposed to interpret the pathogenesis of schizophrenia from the perspective of “

zang

-

fu

organs-

qi

and blood-brain and spirit”， that is， dysfunction of the

zang

-

fu

organs， disharmony of

qi

and blood， and malnourishment of the brain

ti

lead to dysfunction of the spirit

ti

and

yong

. In clinical practice， treatment of schizophrenia can be divided into four stages， for which the method of treating

ti

and

yong

simultaneously is suggested. In the prodromal stage，

Liuwei Dihuang Decoction

combined with

Sini San

（六味地黄汤合四逆散） with modifications is used to nourish the kidney and boost marrow， soothe the liver and rectify the spleen. For acute exacerbation with binding of phlegm and heat syndrome，

Zhaoshi Yikuang Decoction

（赵氏抑狂汤） with modifications is used to clear heat and dispel phlegm， awaken the brain and calm the mind. For phlegm-heat damaging

yin

pattern，

Mengshi Guntan Pill

combined with

Zengye Decoction

（礞石滚痰丸合增液汤） with modifications is used to clear heat and dispel phlegm， enrich

yin

and calm the mind. For the chronic treatment stage，

Yudian Decoction

（愈癫汤） with modifications is used to disperse phlegm and dissolve stasis， move

qi

and awaken the mind. For the rehabilitation and regulation stage，

Shenan Pill

（神安丸） with modifications is used to boost

qi

and nourish

yin

， and tranquilize the mind.