This article explored the treatment of laryngopharyngeal reflux disease （LPRD） from the perspective of ascending and descending of

qi

. It is believed that the disorder of

qi

movement of the middle

jiao

（焦） is the key to the pathogenesis of LPRD. The ascending and descending disorder of liver and lung is an important factor in its prolongation and progression. The treatment of LPRD should follow the nature of the spleen and stomach， with the focus on fortifying and transporting the spleen and the stomach， supplemented by soothing the liver and diffusing the lung. The herbs such as Cangzhu （

Rhizoma Atractylodis

）， Fuling （

Poria

）， Yiyiren （

Semen Coicis

）， Gegen （

Radix Puerariae Lobatae

） and Shanyao （

Rhizoma Dioscoreae

） could be used for fortifying and circuiting the center earth， and Chaihu （

Radix Bupleuri

）， Muxiang （

Radix Aucklandiae

）， Zhiqiao （

Fructus Aurantii

） and Baishao （

Radix Paeoniae Alba

） for soothing the liver and nourishing the blood to harmonize the ascending and descending. Jiegeng （

Radix Platycodonis

） and Xuanfuhua （

Japanese Inula Flower

） are supplemented to diffuse and direct lung

qi

downward thereby mediating the center

jiao

. In this way， the

qi

movement of the spleen and stomach is restored， and the ascending and descending between the liver and lung are harmonized， and therefore the disease is cureda.