ZHANG Yi,XIE Zhijun,HUANG Lin,et al.Mechanism Evolution of Latent Toxin in Systemic Lupus Erythematosus and Syndrome Differentiation and Treatment[J].Journal of Traditional Chinese Medicine,2024,65(16):1721-1724.
ZHANG Yi,XIE Zhijun,HUANG Lin,et al.Mechanism Evolution of Latent Toxin in Systemic Lupus Erythematosus and Syndrome Differentiation and Treatment[J].Journal of Traditional Chinese Medicine,2024,65(16):1721-1724.DOI: 10.13288/j.11-2166/r.2024.16.016.
It is proposed that the disease mechanism evolution of systemic lupus erythematosus can be summarized into four stages: initial invasion and latency, the pathogenesis remains concealing; latent toxin accumulation, the disease gradually becomes apparent; active toxin begins damaging, the disease manifests aggressively; damage resulting to deficiency, the disease course prolonged. Based on the stages of latent toxin evolution, the syndrome differentiation and treatment of systemic lupus erythematosus can be summarized as follows: during the initial latent stage, characterized by latent dampness and heat stagnation, modified
Sanren Decoction
(三仁汤) should be used; in the toxin outbreak stage, marked by intense heat toxin, modified
Xijiao Dihuang Decoction
(犀角地黄汤) combined with modified
Qingwen Baidu Decoction
(清瘟败毒饮) should be used; during the toxin damage stage, which presents as latent toxin damaging