To summarize the experience of Professor WANG Qingguo in diagnosing and treating wind-cold-dampness arthralgia based on the principle that "the nutrient-defense

qi

does not merge with wind-cold-dampness

qi

， so it did not result to arthralgia". By analyzing the relationship between nutrient-defense

qi

and wind-cold-dampness arthralgia， it is believed that the occurrence of wind-cold-dampness arthralgia is closely related to the movement of nutrient

qi

and defense

qi

， and the key to the treatment of this disease is to regulate nutrient

qi

and defense

qi

and remove the combination of nutrient-defense

qi

and wind-cold-dampness

qi

. The core pathogenesis of wind-cold-dampness arthralgia in the early stage is the initial combination of nutrient-defense

qi

and wind-cold-dampness

qi

， and the treatment should harmonize nutrient-defense

qi

and eliminate the pathogen and release pathogenesis， with

Chaihu Guizhi Decoction

（柴胡桂枝汤） as the main prescription； the core pathogenesis of the middle stage is nutrient-defense

qi

and wind-cold-dampness

qi

cemented together， and the treatment should harmonize and tonify nutrient

qi

and defense

qi

and separate the pathogen to alleviate disease， with self-prescribed

Chuanteng Tongbi Decoction

（穿藤通痹汤） as the main prescription； the core pathogenesis of the late stage is deficiency and stagnation of nutrient-defense

qi

， wind-cold-dampness

qi

still exist， and the

treatment should tonify and free nutrient

qi

and defense

qi

to eliminate pathogen and arthralgia， with self-prescribed

Chuanqing Haijia Decoction

（穿青海甲汤） plus

Duhuo Jisheng Decoction

（独活寄生汤） as the main prescription.