中国中医科学院西苑医院,北京市海淀区西苑操场1号,100091
13810665578@163.com
收稿:2024-04-11,
修回:2024-06-19,
纸质出版:2025-01-17
移动端阅览
史宇思,范乐.中医药分阶段防治宫颈癌思路初探[J].中医杂志,2025,66(02):193-196.
SHI Yusi,FAN Le.Ideas of Staged Prevention and Treatment of Cervical Cancer by Traditional Chinese Medicine[J].Journal of Traditional Chinese Medicine,2025,66(02):193-196.
史宇思,范乐.中医药分阶段防治宫颈癌思路初探[J].中医杂志,2025,66(02):193-196. DOI: 10.13288/j.11-2166/r.2025.02.015.
SHI Yusi,FAN Le.Ideas of Staged Prevention and Treatment of Cervical Cancer by Traditional Chinese Medicine[J].Journal of Traditional Chinese Medicine,2025,66(02):193-196. DOI: 10.13288/j.11-2166/r.2025.02.015.
根据宫颈癌的病机变化,认为中医药可从以下三个阶段进行有效防治:持续性高危型人乳头瘤病毒(HR-HPV)感染阶段,此阶段尚无宫颈病变形成,可归为未病状态,宜未病先防,病机为肝郁脾虚、湿浊内蕴,可选完带汤加减以健脾疏肝、益气祛湿;子宫颈低级别鳞状上皮内病变(LSIL)伴持续性HR-HPV感染阶段,即既病状态,宜既病防变,病机为气血亏损、湿瘀互结,可选用当归芍药散加减,治以健脾柔肝、活血利水;宫颈癌前病变术后及宫颈癌术后阶段,即瘥后状态,宜瘥后防复,病机为虚、瘀、湿并存,尚存少量癌毒,可选用当归芍药散合防己茯苓汤加减,治以益气温阳、活血利水,兼以解毒。
According to the pathological changes of cervical cancer, it is believed that traditional Chinese medicine can effectively prevent and treat through the following three stages. Firstly, during the stage of persistent high-risk human papilloma virus (HR-HPV) infection, the state before disease arises, it is advisable to prevent from arises. The disease mechanism of this stage is liver constraint and spleen deficiency, damp-turbidity retention, and modified
Wandai Decoction
(完带汤) can be used strengthen the spleen and soothe the liver, boost
qi
and dispel dampness. Secondly, at low-grade squamous intraepithelial lesions (LSIL) of the uterine cervix with persistent HR-HPV infection stage, the disease state, should control the development of existing disease, and the disease mechanism of this stage is depletion of
qi
and blood, combined with dampness and stasis. Modified
Danggui Shaoyao Powder
(当归芍药散) can be used to strengthen spleen, soften liver, promote blood circulation and drain water. Thirdly, after the surgery treatment of cervical precancerous lesions or cervical cancer, the post-treatment state, it is advisable to "prevent recurrence after treatment", and the disease mechanism of this stage is co-existing of deficiency, stasis, and dampness with a small amount of cancer toxin. Prescriptions of modified
Danggui Shaoyao Powder
and
Fangji Fuling Decoction
(防己茯苓汤) can be used to boost
qi
, warm
yang
, invigorate blood and drain water, and also resolve toxins.
陈号 , 夏昌发 , 由婷婷 , 等 . 中国女性宫颈癌负担快速上升的原因及其应对措施 [J]. 中华流行病学杂志 , 2022 , 43 ( 5 ): 761 - 765 .
狄江丽 , 张小松 , 赵更力 , 等 . 《子宫颈癌综合防控指南(第2版)》解读 [J]. 中国妇幼卫生杂志 , 2024 , 15 ( 2 ): 1 - 5 .
耿宇宁 , 吴玉梅 , 张为远 . 低级别宫颈上皮内瘤变LEEP锥切术与期待治疗的效果评价 [J]. 中国妇产科临床杂志 , 2015 , 16 ( 3 ): 225 - 228 .
RABASA J , BRADBURY M , SANCHEZ-IGLESIAS JL , et al . Evaluation of the intraoperative human papilloma virus test as a marker of early cure at 12 months after electrosurgical excision procedure in women with cervical high-grade squamous intraepithelial lesion: a prospective cohort study [J]. BJOG , 2020 , 127 ( 1 ): 99 - 105 .
赵岷慧 . 扶正解毒汤治疗宫颈柱状上皮异位伴HR-HPV感染临床观察及对免疫细胞水平的影响 [J]. 湖北中医药大学学报 , 2020 , 22 ( 3 ): 37 - 39 .
林兰 , 汪敏华 , 黄烨 , 等 . 中药易黄汤治疗宫颈高危型人乳头瘤病毒感染的疗效观察 [J]. 海峡药学 , 2021 , 33 ( 3 ): 117 - 119 .
刘倩 , 吴冬梅 , 郑怡真 . 郑怡真从湿热治疗高级别宫颈鳞状上皮内病变临证思路 [J]. 福建中医药 , 2021 , 52 ( 6 ): 46 - 47 .
蒋娜娜 . 健脾固带汤治疗脾虚型HSIL合并HR-HPV感染患者LEEP术后临床疗效观察 [D]. 合肥 : 安徽中医药大学 , 2023 .
冯碧波 , 翟建军 , 蔡昱 , 等 . LEEP术联合芪苓方剂治疗宫颈上皮内瘤变的疗效研究 [J]. 中国生育健康杂志 , 2019 , 30 ( 4 ): 332 - 337 .
蔡卉 , 刘艺 , 徐静静 . 中药八珍汤辅助术后化疗治疗宫颈癌患者的临床疗效及对血清肿瘤坏死因子和免疫球蛋白水平的影响 [J]. 世界中西医结合杂志 , 2020 , 15 ( 12 ): 2281 - 2284 .
李瑞玉 , 吕秀萍 . 同步放化疗联合中药治疗局部晚期宫颈癌的疗效及对生活质量的影响 [J]. 中国肿瘤临床与康复 , 2016 , 23 ( 7 ): 780 - 783 .
PARERIA FR , RAMIREZ PT , BORRERO FM , et al . Abdominal radical trachelectomy for invasive cervical cancer: a case series and literature review [J]. Gynecol Oncol , 2008 , 111 ( 3 ) : 555 - 560 .
邱天 , 庄梦斐 , 张婷婷 . 完带汤治疗持续性高危型HPV感染的疗效及免疫功能的影响 [J]. 时珍国医国药 , 2024 , 35 ( 2 ): 384 - 387 .
任振杰 , 张业 , 梁帅 , 等 . 当归芍药散的临床应用及药理作用研究进展 [J]. 世界中医药 , 2023 , 18 ( 23 ): 3465 - 3472,3477 .
陈湘宜 , 胡欣欣 . 当归芍药散加味治疗盆腔炎患者的临床效果 [J]. 中华全科医学 , 2020 , 18 ( 2 ): 255 - 257,261 .
唐荣霜 , 石洲 , 李晋奇 , 等 . 三棱莪术药对的研究进展 [J]. 实用医院临床杂志 , 2021 , 18 ( 5 ): 226 - 229 .
于翔 , 张帅林 , 刘艺 , 等 . 白花蛇舌草多糖抗肿瘤作用机制 [J]. 河北中医 , 2024 , 46 ( 10 ): 1752 - 1754, 1760 .
杨亚 , 李瑞煜 , 冯五文 , 等 . 薏苡仁多糖提取纯化、结构表征及药理作用研究进展 [J/OL]. 中华中医药学刊 . ( 2024-08-28 )[ 2024-12-18 ]. http://kns.cnki.net/kcms/detail/21.1546.R.20240827.1459.044.html http://kns.cnki.net/kcms/detail/21.1546.R.20240827.1459.044.html .
0
浏览量
0
下载量
1
CSCD
关联资源
相关文章
相关作者
相关机构
京公网安备11010102007558号